Nepar is a combination of Nimesulide and Paracetamol is a anti-inflammatory, analgesic. Available as nimesulide – 100mg and paracetamol – 325mg.
Pharmacodynamic Nimesulide – is an inhibitor of cyclooxygenase so it inhibits synthesis of destructive prostaglandins and spares cytoprotective prostaglandins. Nimesulide appears to exert its effects also through a variety of other mechanisms and involves interference with the production action of mediators other than prostaglandins such as enzymes, toxic oxygen derivatives, cytokines, platelet activating factor and histamine.
Paracetamol – is a valuable central analgesic but weak peripheral anti-inflammatory agent and exhibits agent and exhibits antipyretic